Asthma Children Science

Understanding and Managing Viral-Induced Wheezing in Children: The Role of Parental Knowledge
14-11-2025CONCLUSION: Parents of children with frequent upper respiratory tract infections exhibited greater knowledge related to wheezing management. Enhancing parental education may contribute to improved symptom recognition and management. These findings underscore the need for targeted educational initiatives and future longitudinal studies to explore the long-term impact of parental knowledge on respiratory outcomes.

Effectiveness of a nurse-led educational intervention on caregiver's burden and quality of life in pediatric asthma at a tertiary care center in Tamil Nadu, India
14-11-2025CONCLUSION: Nurse-led education significantly reduces caregiver's burden and enhances the quality of life, especially in resource-limited settings.

Associations between per- and polyfluoroalkyl substances and metabolic dysfunction-associated steatotic liver disease in adolescents and young adults: modifying roles of age, lifestyle factors, and PNPLA3 genotype
13-11-2025Studies in youth on per- and polyfluoroalkyl substances (PFAS) exposure and metabolic dysfunction-associated steatotic liver disease (MASLD) are limited. The study aimed to evaluate associations between PFAS and MASLD risk and the modifying role of age, lifestyle factors, and genetic risk. We analyzed data from two independent cohorts: the Study of Latino Adolescents at Risk of Type 2 Diabetes (SOLAR) following adolescents aged 8-13 years over 6 years (n=162; recruited between 2001-2012); and...

Characterization of Food Protein-Induced Enterocolitis Syndrome among Asian American Children
13-11-2025CONCLUSION: This large pediatric AsA FPIES cohort demonstrates distinguishing features, including a high proportion of egg FPIES and lack of common food co-associations. Understanding these clinical differences may significantly enhance clinicians' ability to diagnosis and manage FPIES among the rapidly growing heterogenous AsA population.

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21
13-11-2025Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers. This study aimed to investigate the association between serum levels of lipocalin-2 (LCN2), soluble suppression of tumorigenicity 2 (sST2), and fibroblast growth factor 21 (FGF21) with asthma severity and to evaluate their predictive value for prognosis. A total...