Astma Kinderen Wetenschap

How we teach children with asthma to use their inhaler: a scoping review protocol.
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How we teach children with asthma to use their inhaler: a scoping review protocol.

Syst Rev. 2020 Aug 11;9(1):178

Authors: McCrossan P, Mallon O, Shields MD, O'Donoghue D

Abstract
BACKGROUND: One reason that asthma remains poorly controlled in children is poor inhaler technique. Current guidelines recommend checking inhaler technique at each clinical visit. However, they do not specify how best to train children to mastery of correct inhaler technique. Currently, many children are simply shown how to use inhalers (brief intervention) which results in less than 50% with correct inhaler technique. The aim of this scoping review is to explore published literature on teaching methods used to train children to master correct inhaler technique.
METHODS: This scoping review will follow the Arksey and O'Malley framework and the Joanna Briggs Institute guidelines. We will search (from inception onwards) MEDLINE, Embase, Scopus, Web of Science, CINAHL and the Cochrane library. We will include quantitative studies (e.g. randomised controlled trials, cohort studies and case-control studies), published from the year 1956 to present, on teaching the skill of inhaler technique to children with asthma. Two reviewers will complete all screening and data abstraction independently. Data will be extracted onto a data charting table to create a descriptive summary of the results. Data will then be synthesised with descriptive statistics and visual mapping.
DISCUSSION: This scoping review will provide a broad overview of currently used educational methods to improve inhaler technique in children with asthma. The analysis will allow us to refine future research in this area by focusing on the most effective methods and optimising them.
SYSTEMATIC REVIEW REGISTRATION: Open Science Framework ( osf.io/n7kcw ).

PMID: 32782012 [PubMed - in process]



Evaluation of cord blood immunoglobulin E and its association with maternal factors in a group of Iranian newborns.
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Evaluation of cord blood immunoglobulin E and its association with maternal factors in a group of Iranian newborns.

J Cell Biochem. 2019 08;120(8):13658-13663

Authors: Fereidouni M, Nami FA, Serki E, Arefi M

Abstract
Allergic disorders are among the most common diseases around the world especially in children. Many factors contribute to the pathogenesis of atopic disorders, but early events during the pregnancy are very important. The aim of this study was to evaluate the level of cord blood immunoglobulin E (CB-IgE) and its association with maternal in a group of Iranian newborns. In a cross-sectional study, 163 pregnant women randomly selected and information about pregnancy and atopy were taken by questionnaire. Blood samples of mothers and matched cord blood were collected and total serum IgE levels were measured by enzyme-linked immunosorbent assay (ELISA) method. To rolling out the possibility of contamination with maternal blood, total IgA was checked for all the cord blood samples. Sixteen percent of mothers had the history of atopic diseases and the mean IgE level was significantly higher in an atopic than nonatopic mothers (241 vs 102, P < 0.001). About 73.9% of cord blood samples, had high IgE level (>0.9 IU/mL). The level of cord blood IgE (CB-IgE) was not significantly different in male and female newborns (2.14 vs 2.15 IU/mL). There was no significant correlation between maternal factors such as age, pregnancy variables, allergens exposure, smoking, and maternal IgE with cord blood IgE. The results of this study showed that CB-IgE is high in a remarkable number of samples; independent of maternal or fetal factors. Further studies need to evaluate the reasons for the high level of IgE in cord blood in our area.

PMID: 30937964 [PubMed - indexed for MEDLINE]



Assessing children's readiness to carry and use quick-relief inhalers.
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Assessing children's readiness to carry and use quick-relief inhalers.

J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1673-1675.e2

Authors: Volerman A, Toups M, Hull A, Dennin M, Kim TY, Ignoffo S, Sharp LK, Press VG

PMID: 30529064 [PubMed - indexed for MEDLINE]



Epinephrine use in Austin Independent School District after implementation of unassigned epinephrine.
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Epinephrine use in Austin Independent School District after implementation of unassigned epinephrine.

J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1650-1652.e4

Authors: Neupert K, Cherian S, Varshney P

PMID: 30445190 [PubMed - indexed for MEDLINE]



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