Obesity Science

Evaluation of cardiotoxicity following breast cancer irradiation in an Asian cohort in real-world settings
24-09-2025CONCLUSIONS: Major CV events incidences following RT in this Asian cohort with low baseline CVD risk were modest. However, the impact was more pronounced in patients without baseline CVD risk factors, emphasizing the need for personalized risk assessment in RT planning.

Vagotomy improves brown adipose tissue morphology and reduces steatosis in obese mice
24-09-2025The abolishment of vagal abdominal afferents and efferents inputs through vagotomy has been shown to prevent obesity. However, it is unknown whether such a strategy, performed after obesity installation, may treat, or ameliorate obesity and its comorbidities. Here, we aimed to verify the effects of subdiaphragmatic vagotomy on obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) in obese mice that continued to be fed an obesogenic diet after the operation. Obesity was...

Comparison of Early Postoperative Outcomes and Reimbursement Metrics in Obese Versus Nonobese Patients Undergoing Secondary Reconstruction for Achilles Tendinopathy
24-09-2025CONCLUSION: Our findings suggest that secondary reconstruction for Achilles tendinopathy can be done safely in obese patients without increasing short-term postoperative complication rates. Compensation metrics remained comparable between the obese and nonobese groups, indicating that the increased preoperative burden and surgical demands in obese patients may not be matched by a proportional increase in reimbursement.

Differential effects of a stakeholder-informed intensive perinatal eHealth behavioral weight gain intervention between non-Hispanic Black and non-Hispanic White individuals: a secondary analysis of a randomized clinical trial
24-09-2025CONCLUSIONS: This multicomponent eHealth lifestyle intervention effectively attenuated GWG and lowered incidence of preterm birth in non-Hispanic Black but not non-Hispanic White participants, suggesting potential for mitigating racial disparities in pregnancy health.

Impact of a 24-Week Mobile App-Based Human Coaching Program on Body Composition and Lipid Metabolism in Breast Cancer Survivors With Overweight or Obesity: Single-Arm Prospective Cohort Study
24-09-2025CONCLUSIONS: This study demonstrated that a 24-week mobile app-based human coaching program is beneficial for controlling body weight, BMI, triglyceride, and body composition in terms of bioimpedance for breast cancer survivors who are excessively overweight or have obesity.