Obesity Science

CIDEA expression in SAT from adolescent girls with obesity and unfavorable patterns of abdominal fat distribution
21-10-2021CONCLUSIONS: Reduced expression of CIDEA in girls with high VAT/(VAT+SAT) is associated with adipocyte hypertrophy and insulin resistance.

Robust estimates of heritable coronary disease risk in individuals with type 2 diabetes
21-10-2021Type 2 diabetes (T2D) is an important heritable risk factor for coronary artery disease (CAD), the risk of both diseases being increased by metabolic syndrome (MS). With the availability of large-scale genome-wide association data, we aimed to elucidate the genetic burden of CAD risk in T2D predisposed individuals within the context of MS and their shared genetic architecture. Mendelian randomization (MR) analyses supported a causal relationship between T2D and CAD [odds ratio (OR) = 1.13 per...

Longitudinal patterns of urinary incontinence and associated predictors in women with type 1 diabetes
21-10-2021CONCLUSIONS: UI is a dynamic condition in women with T1D. Varying risk factors observed for the different phenotypes of UI suggest distinctive pathophysiological mechanisms. These findings have the potential to be used to guide individualized interventions for UI in women with diabetes.

Comorbidities, poverty and social vulnerability as risk factors for mortality in pregnant women with confirmed SARS-CoV-2 infection: analysis of 13 062 positive pregnancies including 176 maternal deaths in Mexico
21-10-2021CONCLUSIONS: Our study, which is the largest prospective consecutive cohort to date, has confirmed that advanced maternal age, diabetes, hypertension, obesity, very high social vulnerability, and low socioeconomic status are risk factors of COVID-19-related mortality This article is protected by copyright. All rights reserved.

Tonsillectomy for Obstructive Sleep-Disordered Breathing: Should They Stay, or Could They Go?
21-10-2021CONCLUSIONS: In conclusion, all children in our study who are off oxygen within 3 hours of surgery and passed a SRAC were safe for discharge from a respiratory standpoint regardless of age, obesity status, asthma diagnosis, and obstructive apnea/hypopnea index. Additional investigations are necessary to confirm our findings.

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Illness perception in patients with D.M. type II in Cambodia
This research is a qualitative study of illness perception in patients registered in a clinic in a rural area in Cambodia (Cambodia-Dutch Organization). All patients in the clinic with Diabetes...
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