Depressie Wetenschap
Use of the Brain Care Score to Estimate the Risk of Incident Cerebrovascular Events in Middle-Aged Women
16-05-2025BACKGROUND AND OBJECTIVES: In the United States, stroke is the third leading cause of death among women, with 1 in 5 women aged 55 to 75 years expected to experience a stroke. The Brain Care Score (BCS) is an evidence-based tool designed to motivate lifestyle changes, with higher scores associated with reduced risk of stroke, dementia, and depression. We aim to measure the association of the BCS and incident cerebrovascular events (CVEs), including stroke and transient ischemic attack (TIA), in...
16-05-2025BACKGROUND AND OBJECTIVES: In the United States, stroke is the third leading cause of death among women, with 1 in 5 women aged 55 to 75 years expected to experience a stroke. The Brain Care Score (BCS) is an evidence-based tool designed to motivate lifestyle changes, with higher scores associated with reduced risk of stroke, dementia, and depression. We aim to measure the association of the BCS and incident cerebrovascular events (CVEs), including stroke and transient ischemic attack (TIA), in...
Health Maintenance in Postmenopausal Women
16-05-2025There are unique considerations for preventive care in postmenopausal women. Cardiovascular disease is the leading cause of death for women in the United States, and postmenopausal women should be routinely screened for risk factors such as diabetes, hypertension, and dyslipidemia. Atherosclerotic cardiovascular disease 10-year risk scores should be calculated to guide management of risk factors, including lifestyle changes and medications, particularly statins. Average-risk women should be...
16-05-2025There are unique considerations for preventive care in postmenopausal women. Cardiovascular disease is the leading cause of death for women in the United States, and postmenopausal women should be routinely screened for risk factors such as diabetes, hypertension, and dyslipidemia. Atherosclerotic cardiovascular disease 10-year risk scores should be calculated to guide management of risk factors, including lifestyle changes and medications, particularly statins. Average-risk women should be...
Sexual functioning in patients with inflammatory bowel diseases (IBD): prevalence, predictors, and potential benefits of cognitive behavioral therapy (CBT)
16-05-2025CONCLUSIONS: Impairments in sexual functioning are common in IBD patients, which appears in part related to depressive symptoms. Addressing sexual problems in clinical care is crucial, and this study provided preliminary evidence that 'IBD-specific CBT' directed at mental health outcomes, such as depressive complaints, can parallelly help to alleviate sexual dysfunction.
16-05-2025CONCLUSIONS: Impairments in sexual functioning are common in IBD patients, which appears in part related to depressive symptoms. Addressing sexual problems in clinical care is crucial, and this study provided preliminary evidence that 'IBD-specific CBT' directed at mental health outcomes, such as depressive complaints, can parallelly help to alleviate sexual dysfunction.
Mu Opioid Receptor Positive Allosteric Modulator BMS-986122 Confers Agonist-Dependent G Protein Subtype Signaling Bias
16-05-2025The mu opioid receptor (MOR) is a G protein-coupled receptor (GPCR) and is responsible for the effects of all medically used opioids. Most opioids activate all inhibitory Gαi/o/z proteins through MOR, initiating signaling events that culminate in a variety of physiological effects such as analgesia, euphoria, and respiratory depression. Gaining a better understanding of how the chemical structure of opioids influences the functional activation profiles of G protein subtypes by MOR is critical...
16-05-2025The mu opioid receptor (MOR) is a G protein-coupled receptor (GPCR) and is responsible for the effects of all medically used opioids. Most opioids activate all inhibitory Gαi/o/z proteins through MOR, initiating signaling events that culminate in a variety of physiological effects such as analgesia, euphoria, and respiratory depression. Gaining a better understanding of how the chemical structure of opioids influences the functional activation profiles of G protein subtypes by MOR is critical...
Projecten
Koken met eigen kinderen - Dieet op de kaartHet buurtcentrum Morschwijck draait al enige tijd een kookclub voor kinderen en een kookclub voor mensen met een verstandelijke beperking. In samenwerking met Cello zal er een kookclub worden gestart...
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Lekker goedkoop koken - Dieet op de kaart
Het project van kerken en andere partners met en voor mensen die door de crisis geraakt zijn en door financiële problemen geen goede voeding...
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Ziekteperceptie bij patiënten met D.M. type II in Cambodja
Deze studie betreft een kwalitatief onderzoek naar ziekteperceptie bij patienten die geregistreerd zijn in een kliniek in een dunbevolkte omgeving in Cambodja (Cambodia-Dutch Organization). Alle...
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