Depressie Wetenschap
Emotional and pain experiences reported by Ukrainian healthcare workers during wartime
09-07-2025CONCLUSION: Conclusions: The pilot study highlights the urgent need for preventive multidisciplinary interventions to address emotional strain and pain among healthcare workers. Tailored support strategies may enhance well-being and professional sustainability in high-stress environments.
09-07-2025CONCLUSION: Conclusions: The pilot study highlights the urgent need for preventive multidisciplinary interventions to address emotional strain and pain among healthcare workers. Tailored support strategies may enhance well-being and professional sustainability in high-stress environments.
Assessing modifiable risk factors for dementia in the Czech Republic: findings from the Survey of Health, Ageing and Retirement in Europe study
09-07-2025The role of modifiable risk factors in the development of dementia in Central and Eastern Europe remains understudied. We aimed to examine the association between 12 risk factors and the incidence of dementia in the Czech Republic and estimate the proportion of new dementia cases that can be attributed to these risk factors. Data of 3805 Czech participants in the Survey of Health, Ageing, and Retirement in Europe (mean age: 70 years, median 6.5-year follow-up) were analyzed. Hazard ratios (HRs)...
09-07-2025The role of modifiable risk factors in the development of dementia in Central and Eastern Europe remains understudied. We aimed to examine the association between 12 risk factors and the incidence of dementia in the Czech Republic and estimate the proportion of new dementia cases that can be attributed to these risk factors. Data of 3805 Czech participants in the Survey of Health, Ageing, and Retirement in Europe (mean age: 70 years, median 6.5-year follow-up) were analyzed. Hazard ratios (HRs)...
Effects of the Thank You-Sorry-Love (TSL) program on psychological and physiological well-being of military spouses
09-07-2025This study examined the effects of the Thank You-Sorry-Love (TSL) program on depression, anger, marital satisfaction, and cortisol levels among military spouses. A total of 18 military spouses were matched and randomly assigned to either an experimental group (n = 9), which participated in the TSL program, or a control group (n = 9), which did not receive the intervention. Depression, anger, marital satisfaction, and cortisol levels (an oxidative stress biomarker) were measured at two time...
09-07-2025This study examined the effects of the Thank You-Sorry-Love (TSL) program on depression, anger, marital satisfaction, and cortisol levels among military spouses. A total of 18 military spouses were matched and randomly assigned to either an experimental group (n = 9), which participated in the TSL program, or a control group (n = 9), which did not receive the intervention. Depression, anger, marital satisfaction, and cortisol levels (an oxidative stress biomarker) were measured at two time...
Microglial BDNF modulates arketamine's antidepressant-like effects through cortico-accumbal pathways
09-07-2025Arketamine, the (R)-enantiomer of (R,S)-ketamine, shows even greater rapid and sustained antidepressant-like effects in rodent models compared to esketamine, yet the underlying mechanisms remain unclear. In this study, we used the chronic social defeat stress (CSDS) model to investigate how arketamine exerts its antidepressant-like effects. We found that activating cAMP response element-binding protein (CREB) at S133 and methyl-CpG-binding protein 2 (MeCP2) at S421 drives the transcription of...
09-07-2025Arketamine, the (R)-enantiomer of (R,S)-ketamine, shows even greater rapid and sustained antidepressant-like effects in rodent models compared to esketamine, yet the underlying mechanisms remain unclear. In this study, we used the chronic social defeat stress (CSDS) model to investigate how arketamine exerts its antidepressant-like effects. We found that activating cAMP response element-binding protein (CREB) at S133 and methyl-CpG-binding protein 2 (MeCP2) at S421 drives the transcription of...
Empowering Caregiver Well-Being With the Adhera Caring Digital Program for Family Caregivers of Children Living With Type 1 Diabetes: Mixed Methods Feasibility Study
09-07-2025CONCLUSIONS: The ACDP intervention improved caregivers' psychological well-being and self-efficacy. These findings highlight the potential of digital solutions to support caregiver mental health and positively influence diabetes management. Future research should explore long-term outcomes and scalability.
09-07-2025CONCLUSIONS: The ACDP intervention improved caregivers' psychological well-being and self-efficacy. These findings highlight the potential of digital solutions to support caregiver mental health and positively influence diabetes management. Future research should explore long-term outcomes and scalability.
Projecten
Koken met eigen kinderen - Dieet op de kaartHet buurtcentrum Morschwijck draait al enige tijd een kookclub voor kinderen en een kookclub voor mensen met een verstandelijke beperking. In samenwerking met Cello zal er een kookclub worden gestart...
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Lekker goedkoop koken - Dieet op de kaart
Het project van kerken en andere partners met en voor mensen die door de crisis geraakt zijn en door financiële problemen geen goede voeding...
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Ziekteperceptie bij patiënten met D.M. type II in Cambodja
Deze studie betreft een kwalitatief onderzoek naar ziekteperceptie bij patienten die geregistreerd zijn in een kliniek in een dunbevolkte omgeving in Cambodja (Cambodia-Dutch Organization). Alle...
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