Obesity Science

Seagrass Enhalus acoroides extract mitigates obesity and diabetes via GLP-1, PPARgamma, SREBP-1c modulation and gut microbiome restoration in diabetic zebrafish
20-06-2025CONCLUSIONS: SEAE exhibits strong anti-obesity and anti-hyperglycemic effects by modulating key metabolic pathways and restoring gut microbial homeostasis. These findings highlight SEAE as a promising marine-derived therapeutic candidate for metabolic syndrome and warrant further investigation as a functional food or nutraceutical.

Trends and economic inequalities in obesity prevalence in Ghana: a cross-sectional study spanning 2008-2022
20-06-2025CONCLUSION: There are pro-rich inequalities in obesity prevalence in Ghana. Wealthier women, particularly those in urban and coastal areas, older age groups, and those with higher parity, are disproportionately affected by obesity. Policies and interventions aimed at reducing economic inequalities in obesity should consider the unique challenges faced by wealthier populations, such as promoting healthier diets and physical activity, while also addressing the broader structural factors that...

Maternal feeding practices and its association with obesity in children: a cross-sectional study in Iran
20-06-2025CONCLUSION: Our results showed that children's BMI or WC was not related to maternal feeding patterns. However, further studies with larger sample sizes and longitudinal design are needed to confirm it.

Digital education and exercise therapy versus minimal intervention for young people at high risk of early onset knee osteoarthritis after ACL reconstruction: a study protocol for the Stop OsteoARthritis (SOAR) randomized controlled trial
20-06-2025BACKGROUND: People who tear their anterior cruciate ligament and have reconstruction surgery (ACLR) are at elevated risk of inactivity, obesity, and early-onset knee osteoarthritis. Consensus recommendations to prevent post-traumatic knee osteoarthritis include person-centered education and exercise-based treatments. The effectiveness of these recommendations is unknown. This study will assess if a digital education and exercise therapy intervention is superior to minimal intervention for...

Inverse association of obesity with bout periodicity in episodic cluster headache: a multicenter cross-sectional study
20-06-2025CONCLUSIONS: BMI and obesity were inversely associated with lifetime bout occurrence and annual bout frequency in ECH, suggesting that neurobiological aspects of obesity may suppress cluster bout periodicity.