Asthma Children Science

Screening Tools in School-Based Health Centers for Children With Asthma
20-06-2025CONCLUSIONS: Home-based asthma triggers for children with asthma who receive care in SBHCs are prevalent. Although complex collaborations are required, SBHCs are a viable site for clinical trials. More research is needed to understand the benefit of interventions in SBHCs to reduce asthma severity.

The impact of asthma education grounded in virtual reality technology upon the quality of life of pediatric patients with bronchial asthma
20-06-2025CONCLUSION: Implementing VR technology - based asthma education for children with bronchial asthma can enhance the asthma control status, effectively mitigate the children's negative emotions, augment medication adherence, and ultimately elevate their quality of life.

Single-cell RNA-sequencing of circulating eosinophils from asthma patients reveals an inflammatory signature
20-06-2025Asthma is the most common chronic lung disorder in the United States. While asthma is heterogeneous, blood eosinophils are central to the pathogenesis in most cases. Yet, the power of modern omics has not been widely applied to the study of asthma eosinophils. We report single cell RNA sequencing of blood eosinophils obtained from patients with severe asthma, mild asthma, and healthy volunteers. The eosinophils from asthma patients showed marked heterogeneity in the population and, as with...

Dupilumab and lymphoma risk among patients with asthma: a population-based cohort study
19-06-2025CONCLUSIONS: Dupilumab treatment was associated with lower all-cause mortality among asthma patients despite increased risk of lymphoma, particularly T and NK cell lymphomas. These findings highlight the need for long-term surveillance and further research into the immunological mechanisms underlying dupilumab-associated lymphoma in asthma.

The effects of prenatal vitamin D supplementation on respiratory and allergy-related outcomes in children: A systematic review and meta-analysis of randomized controlled trials
19-06-2025CONCLUSION: There is moderate-quality evidence suggesting that prenatal vitamin D supplementation has minimal or no significant effect on reducing respiratory tract infections and allergy-related outcomes in children.