Cardiovascular Disease Science

Whole-Genome Duplications in Evolution, Ontogeny, and Pathology: Complexity and Emergency Reserves
27-11-2021Whole-genome duplication (WGD), or polyploidy, increases the amount of genetic information in the cell. WGDs of whole organisms are found in all branches of eukaryotes and act as a driving force of speciation, complication, and adaptations. Somatic-cell WGDs are observed in all types of tissues and can result from normal or altered ontogenetic programs, regeneration, pathological conditions, aging, malignancy, and metastasis. Despite the versatility of WGDs, their functional significance,...

Effects of whole peanut within an energy-restricted diet on inflammatory and oxidative processes in obese women: a randomized controlled trial
27-11-2021CONCLUSION: Our results suggest that the regular intake of the whole peanut as part of an energy-restricted diet showed health benefits since it enhanced body weight loss, besides improving body composition and reducing cholesterol, platelets, and homocysteine concentrations. This article is protected by copyright. All rights reserved.

Interpreting global trends in type 2 diabetes complications and mortality
27-11-2021International trends in traditional diabetes complications (cardiovascular, renal, peripheral vascular, ophthalmic, hepatic or neurological diseases) and mortality rates are poorly characterised. An earlier review of studies published up to 2015 demonstrated that most data come from a dozen high-income countries (HICs) in North America, Europe or the Asia-Pacific region and that, in these countries at least, rates of acute glycaemic fluctuations needing medical attention and amputations,...


Statins: a panacea to reduce mortality in patients undergoing liver transplantation for hepatocellular carcinoma?
27-11-2021In Greek mythology Panacea was the goddess of universal remedy or health. In literary terms a panacea represents a solution to solve all ills and there are few drugs that can claim such an accolade. One drug class that has claimed to be a panacea in adults at increased risk of cardiovascular disease are statins. Since their FDA approval in the late 1980s, statins have revolutionised the management of hypercholesterolemia.

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Illness perception in patients with D.M. type II in Cambodia
This research is a qualitative study of illness perception in patients registered in a clinic in a rural area in Cambodia (Cambodia-Dutch Organization). All patients in the clinic with Diabetes...
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