Cardiovascular Disease Science
Whole-Genome Duplications in Evolution, Ontogeny, and Pathology: Complexity and Emergency Reserves27-11-2021
Whole-genome duplication (WGD), or polyploidy, increases the amount of genetic information in the cell. WGDs of whole organisms are found in all branches of eukaryotes and act as a driving force of speciation, complication, and adaptations. Somatic-cell WGDs are observed in all types of tissues and can result from normal or altered ontogenetic programs, regeneration, pathological conditions, aging, malignancy, and metastasis. Despite the versatility of WGDs, their functional significance,...
Interpreting global trends in type 2 diabetes complications and mortality27-11-2021
International trends in traditional diabetes complications (cardiovascular, renal, peripheral vascular, ophthalmic, hepatic or neurological diseases) and mortality rates are poorly characterised. An earlier review of studies published up to 2015 demonstrated that most data come from a dozen high-income countries (HICs) in North America, Europe or the Asia-Pacific region and that, in these countries at least, rates of acute glycaemic fluctuations needing medical attention and amputations,...
Illness perception in patients with D.M. type II in Cambodia
This research is a qualitative study of illness perception in patients registered in a clinic in a rural area in Cambodia (Cambodia-Dutch Organization). All patients in the clinic with Diabetes... Read