The role of trait anxiety in associative learning during and after an aversive event.
Learn Mem. 2019 Feb;26(2):56-59
Authors: Ilse A, Prameswari V, Kahl E, Fendt M
Trait anxiety is considered to be a risk factor for anxiety disorders. The aim of the present study was to investigate how trait anxiety affects associative learning during and after an aversive event in laboratory rats. For this, rats were first submitted to a light-dark box test, followed by relief, safety, and fear learning. Our data demonstrate that all types of learning were affected by trait anxiety, both on a group and on an individual level. Whereas high levels of anxiety impaired relief and safety learning, fear learning was more pronounced. These findings help to show how trait anxiety might be involved in the etiology of anxiety disorders and pathological sensation- and risk-seeking.
PMID: 30651378 [PubMed - in process]
Anxiety in youth at clinical high risk for psychosis: A case study and conceptual model.
Schizophr Res. 2019 Jan 14;:
Authors: Baer LH, Shah JL, Lepage M
Some individuals identified as being at clinical high risk (CHR) for developing psychosis may suffer substantial anxiety due to a fear of transitioning to psychosis. This can be associated with catastrophic misinterpretation of normal mental experiences, such as a momentary lapse in attention, as markers for psychosis, fueled by hypervigilance for mental experiences that may be perceived as signs of impending psychosis. This anxiety may only worsen due to the self-stigma triggered by admission to a psychiatric CHR clinic, independent of whether or not the individual transitions to psychosis. Based on a clinical case study, we propose a cognitive model for this anxiety, an extension of Clark's model of panic. Our model accounts for causal factors of this distress, such as self-stigma and maladaptive core beliefs. It also includes maintaining factors such as hypervigilance for mental experiences and catastrophic misinterpretation of normal mental experiences as anomalous and portending eventual psychosis. We outline assessment and treatment guidelines and offer suggestions for how this model could be empirically validated. We suggest that treatment with this model, under the neural diathesis-stress framework, may have the potential to lower the risk of transition to psychosis and that assessment for such anxiety should be part of standard CHR care.
PMID: 30651203 [PubMed - as supplied by publisher]
Broadening the fear-avoidance model of chronic pain?
Scand J Pain. 2017 10;17:176-177
Authors: Boselie JJLM, Vlaeyen JWS
PMID: 28988105 [PubMed - indexed for MEDLINE]